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Such a profile might be useful in understanding the molecular mechanisms determining response or resistance and would provide the basis for a predictor of chemotherapy response.
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In contrast to other studies focussing on only gene expression, we evaluated both gene- and exon-level expressions as the basis for a reliable predictor of neuroblastoma outcome.
The top-left panel displays the bi-dimensional surface of the fitted relative risk (RR) in a 3-D graph, predicted for the grid of temperature and lag values, with a reference black line corresponding to the centering value of the basis for the predictor space (here 17°C).
Finally, we show how the resulting binding site predictor can be used as the basis for a classifier that predicts CaM binding proteins, with improved accuracy over earlier work.
Furthermore, urinary NGAL and MMP-9 are useful predictors of the presence of brain tumors and may provide a basis for a novel, non-invasive method to identify new brain tumors and monitor known tumors after treatment[ 31].
These observations also form the basis for a new family of algorithms for finding all physically meaningful solutions and singular points called 'global terrain methods', which consist of a series of downhill, equation-solving computations and uphill, predictor corrector calculations.
The overall modeling strategy we employed involves using the mouse model to first identify those genes that are most relevant to the PBC response to a mammary tumor and then using these genes as the basis for developing a human breast tumor predictor.
The probability distribution of the test statistic (the Mantel r) is generated by this random permutation process and used as a basis for assigning a probabilistic interpretation of the true correlation statistic between the observed response and predictor matrices.
We are proposing a set of eight hypothesized predictors, based on the trust distrust theories that could serve as a basis for developing a PDTD scale.
Here z [ x 0 ] and c [ ℓ 0 ] are the vectors of transformed values of x0and ℓ0 obtained by the application of the sets of basis functions for predictor and lags, respectively.
The objective data collected on adherence provide an excellent basis for further exploration of predictors of adherence and have great value in guiding footwear prescription practice and diabetic foot treatment.
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