Sentence examples for basis and progression of from inspiring English sources

Hence, assessment of mitochondrial health in a dynamic fashion in our aging populations may provide a means for understanding the basis and progression of many forms of age-related diseases, including neurodegenerative diseases, diabetes, cardiovascular disease, liver disease, and cancer.

However, the genetic basis of dedifferentiation and progression of carcinoma cells has not been determined.

Combining these techniques allows the researcher to obtain actual in vivo molecular expression information from the image enabling the study of the molecular basis of initiation and progression of mammary cancer.

The adenoma-carcinoma sequence is the basis for tumorigenesis and progression of CRC, and a number of molecular changes have been identified [ 3].

BBB breakdown is now considered as the basis of initiation and progression of AD, because it reflects abnormal functioning of the BBB that modulates efflux and influx of various molecules including A β. Previously, by using a cerebral endothelial marker in brains of 5XFAD mice, we could observe disrupted cerebral capillaries in the location where amyloid plaques were accumulated.

A plethora of environmental and behavioral factors interact, resulting in changes in gene expression and providing a basis for the development and progression of cardiovascular diseases.

Further investigations are needed to better understand the molecular basis of the onset and progression of Alzheimer's disease.

The development of genetically modified, transgenic or knockout, mouse models has greatly advanced our understanding of the molecular basis of initiation, promotion, and progression of breast cancer.

The anti-cancer efficacy of YM155 in combination with platinum compounds was evaluated on the basis of cell death and progression of tumour xenografts.

Mitochondrial dysfunction is considered to be the basis of the development and progression of several neurologic diseases with different aetiologies, including ND [ 8].

Over the past years, tremendous efforts have been made to elucidate the molecular basis of the initiation and progression of ovarian cancer.