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The differential effect of the two basic subtypes of this class of drug has been well described; lipophilic statins diffuse across cellular membranes and exert their metabolic effects in the liver and other tissues; hydrophilic statins require active transport across the cell membrane in order to exert their actions intracellularly.
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Like C. pneumoniae of human origin [ 25, 26], koala LPCoLN is predicted to encode 21 Pmps that are phylogenetically related to one of six basic subtypes (pmpA, B/C, D, E/F, G/I and H; Additional files 3 and 4) [ 25, 27- 29].
As revealed in Table 1, 6 basic subtypes were identified.
In other words, (i) is there evidence for material entities that cannot be subsumed under one of the three suggested basic types, and (ii) is there evidence documenting the need for differentiation of further subtypes of the suggested basic types?
Our results indicated that the molecular subtypes of DCIS were not related to basic characteristics as histopathological grade and tumor size.
This basic classification has been expanded over the last century with the discovery of new subtypes of cells.
The writer describes the different varieties and subtypes of juggling.
Three subtypes of ADHD were identified in 1994: inattentive, hyperactive-impulsive and combined.
Two subtypes of depression that affect only women -- premenstrual dysphoric disorder and postpartum depression -- occur then.
The categories are not monolithic, she has found; there are several subtypes of female: housewife, career woman, feminist, sex object.
Visudyne, which had worldwide sales last year of $357 million, is approved for only one of three subtypes of macular degeneration.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com