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In this review article we provide a synopsis of basic studies that are of direct relevance to the clinical findings in depression and antidepressant drug action.
In addition to the potential therapeutic uses of these materials, they also provide model systems for basic studies that may shed light on developmental processes.
To conduct basic studies that further define the mechanisms mediating the pathogenesis of severe asthma, particularly those phenotypes characterized by late onset, obesity, steroid-unresponsiveness or non-inflammatory pathways.
It has been repeated proved by clinical and basic studies that obesity would adversely affect cardiac remodeling and heart failure, which is closely related to myocardial lipid metabolic disorder.
Given this information and the assumption from the results of basic studies that the combined use of these two drugs might yield synergistically enhanced efficacy, we carried out a phase I study of weekly nab-paclitaxel in combination with S-1 in patients with HER2-negative MBC.
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This paper presents a generalized basic study that addresses practical needs for an understanding of the major mechanisms involved in the mineralization of groundwater in the Great Bend Prairie aquifer in south-central Kansas.
The objective was to evaluate homeopathic basic research studies that use plant-based bioassays.
We review the recent publications on developing engineering and pharmaceutical agents to alleviate stent related symptoms, and examine basic science studies that may support a particular approach.
Many of the significant advances of the past year were made in basic biology studies that use laboratory rodents and cell cultures as models.
He was the first Director of the Sackler Institute for Developmental Psychobiology at Columbia University, past president of the International Society of Developmental Psychobiology, and author of many basic science studies that laid the ground work for this article.
Although the deposition of amyloid-β (Aβ) peptides and formation of senile plaques in the brain is the cardinal morphological feature identifying the clinical phenotype of AD [3], [4], increasing clinical and basic studies suggest that inflammatory activation of microglia may play an equally important role during the initiation and progression of the disease [5].
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