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Nevertheless, we would like to highlight the importance of assessing immune-circadian connectivity as a further step for translating basic science results into successful randomized controlled trials.
This review addresses successes, but also questions, challenges, and chances regarding the translation of basic science results into clinical practice, i.e. the capability to apply the results of basic and/or clinical research in order to design therapies suitable to improve patient outcome.
Further research into disrupted PNS insulin signaling relative to other pathogenic mechanisms is needed, as this will be a key step in translating these basic science results into clinical applications.
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Hardly 0.1% of all funded basic science research results in a commercial venture.
"There are a lot of steps that turn basic science into clinically meaningful results," said Karuna Jaggar, executive director of Breast Cancer Action, an advocacy group.
A tiny fraction of these students pursue career in basic science research, resulting in concerns of not having enough number of basic scientists with deep clinical knowledge.
The first level, or T1, entails the movement of results from basic science into the first human clinical trial.
Such an approach is consistent with the current priority in translating basic science knowledge into health applications.
Therefore, proteomics can help translate basic science discoveries into the clinical practice of personalized medicine [ 14– 14].
As such, proteomics can help to translate basic science discoveries into the clinical practice of personalized medicine [ 30, 31].
Although VEGF is a very promising compound, translating the basic science breakthroughs into clinical practice is the major challenge ahead.
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