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Druss et al. [ 8] reports a shift from basic science research to clinical research over the last 20 years of the 20th century.
With the current trend toward development of specific, molecular targeted therapies, the translation of basic science research to clinical medicine is more important than ever.
Equally important is the need to improve clinical translation from basic science research to delivery of interventions, and to ensure global needs inform discovery science agenda-setting.
Basic science research to identify relevant biomarkers is increasing[ 27], but health services research to support the translation of discovery research into effective clinical care is lacking[ 1, 6].
Efforts are underway to improve the process of clinical translational research research moving basic science research to effective clinical interventions ensuring that public investments in basic science research lead to improved individual and population health outcomes.
The sample size was calculated to allow for separate analyses by research type (controlled clinical trials, other clinical research, basic science research), to detect a minimum relevant OR of 2.0 with a power of > 80%.
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More work is needed to improve the instrument for use in basic science research and to assess the applicability to other medical specialties.
Implants are quickly evolving to address the findings of basic science research, sometimes to the detriment of the requirement for long-term results.
Thus, both clinical and basic science research have to be intensified and the translational aspects have to be strengthened in the next decade with the aim of surpassing even the progress seen in the last decade.
Some areas of basic science research continue to see solid funding, including cybersecurity and nanotechnology, as well as imaging and ad hoc networking, according to Kleinrock and Spafford.
Small teleost fish including zebrafish and medaka have been used as animal models in basic science research due to the relative ease of handling and transparency during embryogenesis.
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