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Advances in basic science and preclinical testing have begun to provide a scientific basis for distinguishing arrhythmogenicity from drug-induced QT effects.
Clinical applications of muscle regeneration strategies are very limited although the topic receives a substantial amount of interest in basic science and preclinical studies (Corona and Greising 2016; Kwee and Mooney 2017).
In this review, we will focus on the basic science and preclinical studies that have accelerated the development of decellularized myocardial matrix hydrogels into an emerging novel therapy for treating the heart after a myocardial infarction.
Mouse models provide an excellent resource for study in both basic science and preclinical research.
In early stages of medical education, basic science and preclinical courses are the main components of learning.
Even when disease and drug models build on robust basic science and preclinical testing, in vivo studies in humans represent the only way of confirming or discrediting emerging theories.
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Thus, clinical researchers must balance cost, the strength of basic-science and preclinical data, and feasibility when developing clinical trials.
Despite encouraging results in preclinical (basic science) and clinical studies, improvements in hip survivorship or time to THA has not been uniformly reported and remains controversial [ 2, 8, 14].
Hence we believe that the long-term strategy needed for an intractable problem such as pancreatic cancer requires closer integration between basic science and clinical oncology, including the preclinical testing based on models similar to those used in the present study.
The college curriculum is a traditional structure with two preclinical years of basic science and integrated clinical exposures followed by two clinical years.
In general, medical studies continue to be divided into a preclinical coursework focusing on basic science, and a clinical portion of four years.
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