Sentence examples for basic residues that are from inspiring English sources

In RNase A, arginine 39 is one of the nine basic residues that are believed to form a multisite cationic region involved in protein-RNA interactions [28].

This prong is surrounded by many basic residues that are also conserved in Syndapin homologues (K127, K130, H120, H121, R129, K28, K137, K35, K112; Figure 2C and S1).

The 34-amino acid S1 contains a motif with alternating hydrophobic and basic residues that are thought to be important for the interaction with LPS [ 21].

Consistent with this, binding of RACK1 to ribosomes is compromised by mutation of a number of basic residues that are conserved across the identified RNA binding interface of RACK1 species but that are absent at the cognate sites in Gβ.

The predicted EB1-binding domain in KIAA0774 is rich in serines, proline and basic residues that are commonly conserved in the EB1-binding domain of other +TIPs (Galjart, 2005; Mimori-Kiyosue et al, 2005; Slep et al, 2005); these crucial residues are conserved in KIAA0774 (Fig 1A, asterisk).

When we aligned the NLSs of ZIC3 (ZF2 + ZF3), Glis3 (ZF3 + ZF4) and PacC (ZF2 + ZF3), we could see that the three basic residues that are critical for the ZIC3 nuclear localization (R320, K337 and R350) are conserved among these sequences (Fig.  9).

Three of the five sulfate ions are clustered in a location distinct from the heparin-binding sites of FGF1/2 (Fig. 2D E), but occupy a continuous stretch of basic residues that is, in part, formed by the lysines identified as interacting with heparin by Xu et al. (2012), and could represent an extension of the canonical site.

Close examination of the C-terminal tail of human NOXO1 reveals a region comprising a number of basic residues that is absent in the mouse protein (see Figure 1B) (residues 347 359, ERRPRRQGRPRG).

The classic mono- or bipartite NLS typically contains a cluster of basic residues that is recognized and bound by the NLS receptor importin-α, which is further associated through a separate domain with importin-β [50], [51].

It is indeed important to reiterate (see Introduction) that, while referred to as a Basic region, this region is not particularly enriched in basic residues but rather more lacking in acidic residues, and thus it is very possible that it is some other property besides basic residues that is important for the function of the Basic region.

The N-terminal part contains a stretch of basic residues that is important for membrane association of Dia. - In polarized Drosophila tracheal cells and Madin-Darby canine kidney (MDCK) cells, restriction of Dia to the apical domain is controlled by a combination of these mechanisms.