Sentence examples for basic residues of the from inspiring English sources

The hydrophilic residue Tyr, which sits in the middle of the peptide, is in close proximity to the polar and basic residues of the protein surface.

The known peptide Ala-Ile-His has two hydrophobic and one acidic residues; this peptide can interact with only 50% of the basic residues of the binding region.

Ertapenem has a net negative charge and two carboxylic groups are able to form hydrogen bonds with the basic residues of the channel.

Interhelical salt bridges and charge-stabilized hydrogen bonds between acidic and basic residues of the two monomers are predicted to form an interaction domain, which does not follow the classical knobs-into-holes zipper model.

For instance, the cluster of basic residues of the L1 site is located in close proximity to water/membrane interface and, therefore, this site is probably targeted in the first place.

For the bottom panel of Figure 4, the ZDOCK server was used to calculate the most probable complex of ERK1 [PDB∶2zoqandand HIV MA [PDB∶1uphA] when binding was forced between the basic residues of the Dd motif on MA (Arg22, Lys26, and Lys27) and the CD site of ERK1 (Glu98, Asp179, Asp335, and Asp338 [25]).

However, upon encountering the acidic lumen of the lysosome, the weakly basic residues of these compounds become protonated, preventing them from crossing the lysosomal membrane back to the cytoplasm1,2,3,4.

Amongst the 18 basic residues of this domain, 9 were changed for Ser which removed the 3 typical HP binding clusters (Fig. 1A).

Conversely, mutations in the basic residue of the SlTRM M8 motif reduced the interactions with wild-type OVATE and SlOFP20 (Fig. 2c d).

The one exception is the Langerhans cell protein-1 (LCP1)/KIAA0737 pair, which lacks the second basic residue of the motif.

Here, the first two negative charges may somehow shield the basic residue of the GFP and interfere with the translocon in the PPM.