Sentence examples for basic residue at the from inspiring English sources

Alternatively, as shown for mammalian AMPK and cauliflower HMG-CoA reductase kinase [67], a basic residue at the -4 position in SnRK2 substrates may compensate for a lack of Arg at the -3 position.

An extra basic residue at the N-terminus increased retention significantly.

Using sequence-based annotation analysis, the comparison of the IML2 of UCP1 vs. that of UCP2/3 revealed that all proteins share a basic residue at the N-terminal side of the IML2.

For example, a peptide based on Ser of the Ca+2-ATPase, ACA2 [ 31], can be phosphorylated by CDPKs in vitro but lacks a basic residue at the P − 3 position (See Table 1, motif B).

It also showed a marked preference for peptide substrates with basic residues at the +1 and +3 positions relative to the phosphorylated residue [ 38] (although the main site for eEF2K in eEF2, Thr, only contains a basic residue at the +3 position).

Finally, the basic residue at the 160 position (a lysine for RXR and an arginine for PPAR) are both positioned in order to make moderate interactions with the hydrogen bond acceptors on the central basis step (GT), as usual for canonical DBD HRE contacts at this position.

The presence of a strong basic residue at this position is conserved in all forkhead transcription factors, and it contributes to DNA binding through both hydrogen bonding and electrostatic interactions.

Conversion from an acidic to a basic residue at this site (E1544K) results in a sixfold enhancement of affinity via modification principally of the association rate, with enhanced salt-dependence, decreased entropic barrier and retained specificity.

In most euteleosts, the residues at position 74 were hydrophobic; only medaka LCE contained a basic residue at this position.

As shown in Figure 6, the binding groove presents basic residues at the top of the cavity, acidic residues at its bottom and hydrophobic residues as edges.

c-Raf seems to have a strong preference for basic residues at the −3 position and hydrophobic residues at the +1 position relative the phosphorylated serine/threonine residue.