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Translating insights from basic research into new medicines provides significant benefits to patients and American taxpayers.
The new center aims to translate basic research into new therapies.
The reform-minded government of Japanese Prime Minister Junichiro Koizumi aims to restructure Japan's research and development systems, in an attempt both to funnel basic research into new industrial products and to attract top international talent.
Several pharmaceutical firms, including Alkermes Inc., Parke-Davis, Pfizer, and Novartis, have brought in Mundel to shake up their research and development programs and streamline the process of translating basic research into new drugs.
UM's Interdisciplinary Stem Cell Institute seeks to understand the biology of stem cells and translate basic research into new regenerative therapies.
Converting basic research into new treatments has many names such as translational, clinical, applied, and disease-oriented research, to name just a few.
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Basic research into novel predictive assays, genetic polymorphisms, and new molecular methods to risk-stratify and to determine treatment options for sepsis have occupied much of the Critical Care publications relating to sepsis pathophysiology in 2008.
Japan spends about 7% of its government R&D budget on practical "translational research"—converting basic research into meaningful new manufactured goods and processes.
Beginning in 1980, Congress enacted a series of laws designed to speed the translation of tax-supported basic research into useful new products-a process sometimes referred to as "technology transfer".
The former involves basic research into characterising and validating new targets, mostly proteins, followed by identification of inhibitors or agonists through the use of target-based screening assays and/or in silico drug design.
The Innovative Medicines Accelerator (IMA) is aiming to help basic and applied researchers from across the schools of Medicine, Engineering and Humanities & Sciences translate their basic research discoveries into new therapies and diagnostics, and to carry out fundamental research in humans in support of that goal.
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