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Airway cell cultures are the primary vehicle for basic research and therapeutics development in CF in part due to lack of a widely available animal model.
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The RNA-guided endonuclease CRISPR-associated protein 9 (Cas9), in particular, has attracted attention for its promise in basic research and gene editing-based therapeutics.
While a host of challenges to the broader use of proteins as basic research tools and therapeutics exist, a fundamental obstacle is one that continues to resist a general solution: protein folding.
Owing to their high affinities and specificities, rabbit monoclonal antibodies (mAbs) have demonstrated value and potential primarily as basic research and diagnostic reagents, but, in some cases, also as therapeutics.
There is no doubt that in few years RNAi silencing approaches will become the tool of choice to knock-down genes in all groups of non-mammalian vertebrates, fulfilling different purposes, from basic research to animal therapeutics and drug discovery.
HMF is also important in clinical research and therapeutics.
A new era in the field of FRDA research and therapeutics is beginning.
A new era in the field of DS research and therapeutics is unfolding.
The fact that a commercially-available LF preparation (LF-HMA) that is widely used in basic research studies and for evaluation of vaccines and therapeutics is 3-fold less potent than native LF (LF-A) should be considered when comparing published studies and in the design of future experiments.
We aim to publish research that relates causal and risk factors with neurodegenerative conditions causing dementia, and describes the potential therapeutic applications of basic research, animal models, and other model systems, and novel therapeutics.
This sponsored feature will provide the reader with an update on the state of scientific research in the region and a glimpse into the powerful engine that is driving progress there, from basic research to the commercialization of therapeutics and medical devices.
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