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In addition, we discuss recent applications of peptides to regulate protein protein interactions for both basic research and therapeutic purposes.
The specificity of RNA-guided nucleases has gathered considerable interest as they become broadly applied to basic research and therapeutic development.
Overall, single protein, FMOD-based, cell reprograming bypasses the risks of mutation, gene instability, and malignancy associated with genetically-modified iPS cells, and provides an alternative strategy for engineering patient-specific multipotent cells for basic research and therapeutic application.
The use of viral vectors for gene delivery offer many advantages for both basic research and therapeutic application through the continuous expression of a gene product within a target region.
Our results demonstrated successful rational modification of AAV2 as a targeting delivery vehicle, establishing a facile platform for precision engineering of virus-based nanoparticles in basic research and therapeutic applications.
Furthermore, DIFs may modulate mammalian chemotaxis via PDE1 or other PDEs; if so, some DIF derivatives might be utilized as drugs to control mammalian chemotaxis for basic research and therapeutic purposes.
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Control of cell surface nanoarchitectures has attracted attention as a process that can be used in both basic research and for therapeutic applications.
Efficient transduction and long-term stable expression of transgenes is achieved with the help of lentiviral transfer vectors both for basic research and gene therapeutic approaches [27].
Protein protein interactions (PPIs) involving gankyrin are of great interest in basic research and as therapeutic targets.
A large amount of evidence has proven the pervasive power of this notion, both in basic research and in therapeutic applications.
The development and use of molecular techniques to display proteins on the surface of filamentous phage (phage display) reported in 1985 soon inspired scientist to build up an innovative technology for the selection of antibody fragments and ultimately for the development of monoclonal antibodies for basic research and diagnostic and therapeutic purposes.
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