But overall the Clinton agenda mixes unlikely promises for significantly increased federal spending in education, basic research, and infrastructure with more specific reforms in such hot-button areas as immigration, intellectual property, and tech infrastructure.
Participants were challenged to think broadly and beyond their basic research foci and specific areas of expertise, identifying means to facilitate integration and interaction with clinicians and public health practitioners.
But that investment must truly be in basic research and not tied to the applications of any specific company, industry or social goal, no matter how laudable.
That paradigm prompted the pharmaceutical industry to focus on development of drugs targeting specific molecular components, funding basic research, and technological applications in line with those premises, thus strengthening a bottom-up reductionist approach.
Overall, single protein, FMOD-based, cell reprograming bypasses the risks of mutation, gene instability, and malignancy associated with genetically-modified iPS cells, and provides an alternative strategy for engineering patient-specific multipotent cells for basic research and therapeutic application.
Encouragingly, darapladib, an orally Lp-PLA2 specific inhibitor, has been tested in basic research and preclinical trials and the outcomes are quite striking.
Titanium, a smart biomaterial with specific characteristics, has been used frequently in both basic research and medical devices.
Site-specific recombinases are valuable tools for myriad basic research and genome engineering applications.
