Sentence examples for basic research and animal from inspiring English sources

Short peptides derived from interaction sites between each PKC isozyme and its receptor for activated C kinase act as highly specific inhibitors and have become available as selective drugs in basic research and animal models of human diseases, such as myocardial infarction and hyperglycemia.

Despite the fact that their use is complicated by immunologic incompatibility and possible development of teratomas [ 39- 41], as well as the existence of ethical problems in human application, in the future, the establishment of ESCs lines from ungulates could allow their employment in bulk for basic research and for producing animal models of human diseases [ 42].

Basic research and the combination of reliable animal inoculation models, reverse genetics and computational biology tools will allow the rational design of safe and effective FMD vaccines.

These powerful tools have greatly facilitated the generation of plant and animal models for basic research, and harbor an enormous potential for applications in biotechnology and gene therapy.

Through their capacity to confer an increase in the proportion of integration events that are productive, together with improvements in the level of transgene expression, RNP CpG island vectors have many other potential applications, including use in mammalian cell-based in vitro screens for drug discovery, transgenic animals for basic research and drug discovery, and gene therapy.

Consistent with these results, basic research studies and animal data demonstrated that vitamin D receptors exist on peripheral nerves and Schwann cells, and consequently, vitamin D could promote production of nerve growth factor and axon regeneration in peripheral nerves (Neveu et al. 1994; Cornet et al. 1998; Chabas et al. 2008).

Moreover, in vivo optical imaging contributes towards the reduction in the number of animals used in basic research and drug development.

We believe that since zoonoses can infect both animals and humans, both the medical, public health, basic research and veterinary communities will definitely benefit from this unified resource.

Airway cell cultures are the primary vehicle for basic research and therapeutics development in CF in part due to lack of a widely available animal model.

In this review, we focus on the current state of the art of MALDI-IMS, describe basic technological developments for MALDI-IMS of animal and human tissues, and discuss some recent applications in basic research and in clinical settings.

We aim to publish research that relates causal and risk factors with neurodegenerative conditions causing dementia, and describes the potential therapeutic applications of basic research, animal models, and other model systems, and novel therapeutics.