The bZIP TFs are characterized by a 40- to 80-amino-acid-long conserved domain (bZIP domain) that is composed of two motifs: a basic region responsible for specific binding of the TF to its target DNA, and a leucine zipper required for TF dimerization [5], [25].
A highly conserved bZIP domain consisting of a basic region responsible for DNA binding and three heptad leucine repeats related to TF dimerization [ 23] was observed near the C-terminus of PtrABF, indicating that PtrABF encoded a bZIP family protein.
These data confirm that the central region of C2-L1Tc conthening the upstream-finger and the basic RRR and RRRKEK stretches are the main regions responsible for the binding of the protein to RNA.
The GP practices are arranged into four regions, responsible for planning and commissioning health care.
The basic region is responsible for nuclear localization and DNA binding specifically, and the following leucine zipper motif consisting of several repeats of leucine or other hydrophobic amino acids and grant for recognition and dimerization specificity [ 9].
Of all the senses, she said, it is the only one that bypasses the conscious parts of the brain and goes directly to the limbic system, the region responsible for basic memory, motivation and emotion.
Chris's behaviors were entirely reflexive, he said; they were produced by his brainstem, which regulates basic functions like breathing and body temperature, not by his cortex, the region responsible for higher-order thinking.
