Sentence examples for basic region required from inspiring English sources

We used the same assay to determine the sequences within the HCF-1N Basic region required to support tsBN67 cell proliferation at 40°C.

Surprisingly, much like the transcriptional activation domains of sequence-specific DNA-binding transcription factors, there is no unique sequence within the Basic region required for promoting cell proliferation or G1-to-S phase transition.

These results indicate that, as for tsBN67-cell proliferation, the Basic region is required for full G1-to-S phase progression in HeLa cells.

DNA-binding is mediated by the basic region and requires dimer formation of two AP-2 proteins via the helix-span-helix motifs.

It was shown in [ 30] that the minimal region required for specific DNA binding includes the single zinc finger and two basic regions on either side of the ZF domain.

It is using this colony-formation assay that Wilson et al. [10] showed that the HCF-1N subunit is sufficient and that the HCF-1N Kelch domain and Basic region are each required to rescue tsBN67-cell growth at 40°C.

Nevertheless, the N-terminal basic region of MA does seem to be required for maximum infectivity.

The basic region of the Diaphanous-autoregulatory Domain (DAD) is required for autoregulatory interactions with the Diaphanous-related formin inhibitory domain.

Mutational analysis revealed that membrane recruitment of SLP65 requires both the N-terminal basic region and the C-terminal SH2 domain (Kohler et al, 2005; Abudula et al, 2007).

These two assays identify different requirements for the Basic region.

Likewise, the M2-dependent down-modulation of the STAT pathway requires a scattered motif distributed between the central basic region and N-terminal acids acids of M2 [36], [36].