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After the deletion of the flanking basic region, the RBM25 PWI domain was unable to bind to RNA/DNA, meaning that the flanking basic region is essential for RNA/DNA binding.
These results reveal that the flanking basic region is essential for the nucleic-acid-binding activity of the PWI domain, indicating that this flanking basic region acts as a co-operative partner to facilitate the stable binding of the PWI domain to nucleic acids.
Similar(58)
The basic region is also essential for oxidative stress-inducible transcription of CUP1 by Hsf1.
The basic region was 15 amino acids long and typically included six basic residues.
These results suggest that there is no individual sequence element within the Basic region that is essential for HCF-1N-subunit rescue of the tsBN67 cell-proliferation defect.
Because strong cities are the building blocks of strong regions, and strong regions are essential for a strong America".
Understanding basic economics is essential for being an intelligent voter.
Henhouses must be rebuilt or refurbished, and basic sanitation is essential.
Assuring that publications meet basic standards is essential.
Proficiency in basic skills is essential.
Basic research is essential to this task.
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