Sentence examples for basic region and the from inspiring English sources

Sequence-specific interactions are proposed between the basic region and the invariant cis elements that all bHLH-Zip proteins bind.

The bHLH domain contains approximately 60 amino acids with two functionally distinct regions, the basic region and the HLH regions [ 4].

Previous reports demonstrated that both of the core basic region and the hinge region determine the binding specificity of bZIP TFs [ 45, 46].

Experiments of mutant proteins demonstrated that binding specificity is determined by the core basic region and the hinge region independently, and the two regions have an additive effect on DNA-binding specificity.

Mutational analysis revealed that membrane recruitment of SLP65 requires both the N-terminal basic region and the C-terminal SH2 domain (Kohler et al, 2005; Abudula et al, 2007).

Motif 1 is the basic region and the hinge of the bZIP domain; whilst motif 5 (typically), 3 and 9 represent the variable motifs in the leucine zipper region across the bZIP gene family.

These results suggest that there are multiple binding sites for Sin3a on the HCF-1 Basic region and that its association with the HCF-1 Basic region correlates with the ability of this region to support G1-to-S phase progression in the HeLa-cell assay.

Although heparin has not been implicated in binding to Slit2 D4, the large basic regions and the conspicuous sulphate-binding site suggest a possible interaction.

We have determined the contact residues in the flanking basic region and in the PWI domain involved in RNA/DNA binding and characterized a nucleic-acid-binding surface in the RBM25 PWI domain that is entirely different from that in the SRm160 PWI domain.

Pattern f lacks any intron in the basic region and in the hinge region.

The resulting alignment is only 66 amino acids long and corresponds roughly to the basic region and helixes of the bHLH domain and to the carboxy-terminal domain.