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HMGA1 is a small basic protein that binds to adenine-thymine (A-T) rich regions of DNA and functions mainly as a specific cofactor for gene activation [ 9].
AGP is the principal basic protein that binds to drugs with significant clinical implications to control the inflammation cascade in the body [ 47, 48].
mAb C is a basic protein that binds to DNA through ionic interaction allowing exogenous DNA to be linked specifically to sperm.
Antigen inhalation activates eosinophils, causing release of major basic protein that binds to and inhibits neuronal M2 muscarinic receptors leading to airway hyperreactivity (Fryer and Jacoby 1992; Jacoby et al. 1993).
HIV-1 transcriptional activator (Tat) is a small (~11 kDa) basic protein that binds to the transactivation-response element (TAR) on the nascent viral RNA and recruits molecular components for efficient transcriptional elongation.
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Histones are highly basic proteins that bind tightly to the acidic DNA to form chromatin.
A double peak at 23/23.5 kDa was found in the resin flow-through ('pH 9 fraction') from the 'high' sample but was less intense in the pH 9 fraction from the 'low' sample indicating that our biomarker is a basic protein that does not bind to the resin under these conditions.
Humans and octopuses both have a gene for a protein that binds serotonin to brain cells.
The galaxin-like proteins, with their two distinct domains, may combine the functions of two distinct classes of mollusc proteins – the acidic proteins that are thought to actively control mineralisation, and basic proteins that either bind bicarbonate or form links with the organic matrix.
All reported members of this family are basic proteins that exist as homodimers in solution and bind to DNA and/or RNA without apparent sequence specificity in vitro.
The identification of the Basic PentaCysteine (BPC) proteins that bind GA repeats, or possibly purine-rich sequences, and the presence of multiple GA repeats within the POS9 region suggest a potential binding of the BPC proteins to affect P-INO expression [ 12, 25].
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