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In large measure, the vulnerability of the fetus and neonate reflects interference with basic processes of neural cell replication and differentiation, culminating in aberrant synaptic function and associated behavioral deficits (Barone et al. 2000; Pope 1999; Rice and Barone 2000; Slotkin 2004).
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We established assays suitable for detecting disturbances in basic processes of brain development by employing human neural progenitor cells (hNPCs), which grow as neurospheres.
As a model of neural development, we employed primary fetal human neural progenitor cells (hNPCs), which are cultured as neurospheres and mimic basic processes of brain development in vitro: proliferation, migration, and differentiation.
This questionnaire measures 10 basic processes of change.
Figure 3 Basic process of pattern matching.
Algorithm ?? describes the basic process of building a classification tree.
The basic process of splicing is conserved among eukaryotic species.
Learn the basic process of a payday loan.
In turn, the diversity of these targets suggests that the organophosphates disrupt some very basic processes in neural cell differentiation.
Embryonic neural stem cell (NSC) cultures provide a valuable tool to study the fundamental processes of neural differentiation.
Many of these functional categories were common to both regions of the brain and represented basic processes that are crucial for general neural function (for example, morphology of nervous tissue, neuritogenesis, guidance of axons, and morphology of dendritic spines).
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