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The nature of surface Lewis and Brønsted acid sites present in supported metal oxide catalysts are determined by adsorbing basic probe molecules like pyridine.
The use of different basic probe molecules whose IR spectra are sensitive to protonation and/or to the strength of Lewis acid base interaction is described.
The basic probe pattern on the microarrays consisted of two PC, six NC, and four CK, which could be used as the position reference and landmarks for image analysis.
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CO, pyridine and lutidine have been used as molecular basic probes.
Moreover, acidic and basic probes may form adducts which are adsorbed on target substrates in order to establish an indirect measure of polarity, acidity, basicity or hydrogen bonding.
Small molecule modulators of epigenetic processes are currently sought as basic probes for biochemical mechanisms, and as starting points for development of therapeutic agents.
We first consider the basic CDIsp probing scheme for the single-user CR system as shown in Fig. 1.
We first present the system model in Section 2. In Section 3, we propose the basic CDIsp probing scheme under the single-user CR system.
For each basic 25-mer probe described above, we generated various probes by changing their length, mismatch position, and type of mismatched nucleotide as follows.
Collectively, there were 738 probes of various sequences (36 PMs and 702 MMs) for each basic 25-mer probe sequence.
Although we improved the chip design for the use in the prototype of the sensor probe, basic design was the same with that by Fukuhara et al. (2011).
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