The fruit fly Drosophila has contributed significantly to our general understanding of the basic principles of signaling, cell and developmental biology, and neurobiology.
As a foundation, the basic principles of dynamic cell sizing are reviewed in Section 2, leading to the motivation for the new IPCAM.
For these reasons, the ESCs have emerged as a unique in vitro experimental system for the investigation of basic principles of mammalian cell differentiation and development.
Although the model oversimplifies many aspects of angiogenesis, it illustrates some basic principles of how cell-ECM interactions can coordinate collective cell behavior during branching growth.
What if you push the envelope a bit more and question the basic principles of what a cell phone actually does?
The basic principle of 3D cell cultures is to provide mammary carcinoma cells with properties that recapitulate in-vivo tumor microenvironment.
Dr. Brenner, who has a trenchant wit and enjoys stirring up the scientific world, had earlier worked on basic principles of how DNA instructs cells to make proteins.
His research career, peppered with landmark discoveries that go all the way from uncovering the basic principles of how DNA instructs cells to make proteins to unraveling the genetic blueprint of the puffer fish, is an indelible part of the history of molecular biology.
A comparison of H2B-GFP-tagged chromatin in live and fixed cells demonstrated these basic principles of nuclear organization also in nuclei of living cells and ruled out fixation artifacts as a major issue.
This study uncovers some of the basic principles of transcriptional response in human cells and expands our understanding of conditional gene expression at the protein network level suggested by earlier studies on tissue-specific gene expression [ 15].
Our real time in vivo imaging of skin epithelium has allowed us to capture a number of basic principles of regeneration including that location dictates stem cell fate, that specialized stem cells are dispensable for tissue growth while the niche is required, and that tissue correction preserves homeostasis.
