Sentence examples for basic pathophysiological mechanisms from inspiring English sources

Based on insights into the basic pathophysiological mechanisms of the disorder, some drugs have been developed which seem promising in early phase II studies (NOS inhibitors and 5HT1F-receptor agonists).

Understanding the basic pathophysiological mechanisms of cognitive decline and how the subcellular organization of signaling molecules is altered with cognitive decline could potentially yield novel therapeutic targets for neuronal aging and neurodegeneration.

The high output state represents one of the basic pathophysiological mechanisms of cardiovascular involvement in these patients.

Thus, in order to improve the knowledge on basic pathophysiological mechanisms of osteoarthritis pain, the characterization of animal osteoarthritis pain models and treatment regimens need to be improved.

As the current study was more focused on basic pathophysiological mechanisms and not (yet) therapeutic interventions, we selected a model without antibiotics for the initial set of experiments.

Thus, if one takes into account the biological limitations of genetic mouse models as surrogates for human disorders, the mdx mouse can be employed as an excellent model system to study basic pathophysiological mechanisms of muscular dystrophy [ 73].

Since AN was induced by a heavy cupula, we concluded that the basic pathophysiological mechanism of PGN is a light cupula in patients with H-BPPV.

Basic research has elucidated many of the pathophysiological mechanisms underpinning secondary damage and many neuroprotective agents have been developed to counteract these mechanisms.

However, the pathophysiological mechanisms remain widely unresolved.

These two disorders share several pathophysiological mechanisms.

The pathophysiological mechanisms leading to migraine chronization remain largely unknown.