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The research should eventually help scientists understand more about basic molecular interactions that will help with the design of pharmaceuticals and other compounds.
The basic molecular interactions required for the signal transduction function of the plasma membrane can be fundamentally understood and conveniently summarized as the cooperative actions of these mesoscale domains, where thermal fluctuations/movements of molecules and weak cooperativity play crucial roles.
These functional "categories" (nucleic acid binding, signal transduction and protein-protein interaction) represent key functions that include control of gene expression, inter-cellular relationships or cellular signaling, and basic molecular interactions of many biological processes.
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Here we propose a conceptual framework, based on recent literature combined with basic principles of molecular interactions, to guide rational design of nanoparticle targeting strategies.
Thus, TF-promoter interactions provide the basic molecular wiring of transcriptional regulatory networks.
Identification of core clock components and their associated molecular interactions has established the basic network architecture of plant clocks, which consists of multiple interlocked feedback loops.
Thus this review outlines our basic understanding of the initial endocrine stimuli and local molecular interactions that regulate mammary branching in rodents as a model for mammary morphogenesis in general.
Cell cultures of parasitic helminths are an invaluable tool for investigations of basic biological processes, as well as for development of improved chemotherapeutic agents and molecular interactions between host and parasite.
Herein we describe the basics of the technology, review the latest applications to the study of molecular interactions involved in cells and new oligonucleotides based assays.
Protein-protein interactions (PPIs) are central to the proper functioning of the most basic molecular mechanisms underlying cellular life, and are often perturbed in disease states.
The observed variety of surface behaviors is attributed to the fine balance of intra molecular interactions caused by the highly branched chain architecture composed of both acidic and basic blocks.
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