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Early in the project, we realized that a basic impediment to good performance would be queries that align well to DNA sequences present with minor variations many times in the genome.
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This study demonstrates the utility of the MM model for determining extravascular transport parameters, and indicates that much of the impediment to diffusion of basic DNA intercalators in tumour tissue may arise from lysosomal sequestration rather than DNA binding.
When all is said and done, the issues in nano-sized devices (individual or arrays) and basic impediments in device operation have not been addressed largely due to not having a perception of end-user requirements, leaving the device's operational bottlenecks unaddressed [3].
Those sectors less heavily invested in the use of TGx for basic research also cited lack of staffing and analytical capabilities as an impediment to broader implementation.
A major impediment to fully realizing the potential of integrating these fields, however, is the lack of basic information about species distribution and richness in nature.
The main impediment to graduation: freshman math.
That is an impediment to political change.
Are drugs an impediment to rebuilding?
That lawsuit was an impediment to reforms".
"It is an impediment to learning".
Transportation was not an impediment to visitation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com