Sentence examples for basic end points from inspiring English sources

But the relative merits of these algorithms are not well understood in terms of their impact on basic end points such as time spent in target and time in hypo- and hyperglycemia.

For the prioritized phase-in substances, the most basic end points for an elementary assessment of toxicity and ecotoxicity will be covered, but for the nonprioritized substances REACH will not provide data for a meaningful hazard assessment of any end point.

Uterotrophic assays were based on the protocol described by Kanno et al. (2003a, 2003b) where the basic end point is uterine weight.

Such models typically model downstream responses as a function of more basic biochemical and genomic end points but do not incorporate the critically needed modeling of the dose responses of these end points.

Because these end points extend beyond the basic processes of brain development, the basic "neurosphere assay" (Breier et al. 2009) cannot detect such changes.

However, progress rarely comes without challenges, and this drive to translate basic-science discoveries into immediate practical end points has raised concerns among many prominent scientists who voice their worries that support for basic-science research may potentially decay.

The novel, nonvalidated end points evaluated by small, basic research studies were not evaluated in the guideline-compliant studies, but any adverse consequences from them, as required for risk assessment, were sought and not found.

Myelin Basic Protein (MBP) antibodies were used to visualize myelin end points and gaps, which are the sites of heminodes and nodes of Ranvier, respectively.

Primary reporting of end points will be based on the basic estimator notion 41 42 controlling for period effects and assuming no period by treatment interactions, including carry-over effects.

Future studies must broaden the basic science approach to endocrine disruption, thereby expanding the mechanisms and endocrine end points examined.

Although the evidence for these three hypotheses is substantial, and end points have been identified in some cases, the ultimate basic mechanisms responsible for perturbations in a given system are unclear.