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Last October, the Nobel Prize for physics, for instance, was shared by French and German scientists for their basic discovery of what is known as the "giant magnetoresistance" effect, which enables much more digital data to be stored on a disk drive.
"It used to be correct, but now with the basic discovery of CPR we've come to understand that the cells inside your body don't become irreversibly 'dead' for hours after you've 'died'… Even after you've become a cadaver, you're still retrievable".
I missed the opportunity to start working in the laboratory of Christian de Duve (who in 1974 would be honored by the Nobel Prize in medicine or physiology, but this was not obvious (yet) around 1960, although de Duve's basic discovery of the lysosomes is going back till 1955).
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He worked out excellent techniques for the experimental manipulation of Neurospora, as well as other microorganisms, and his many basic discoveries of new phenomena set the stage for the development of the field of biochemical genetics.
The contemporary obsession with individual choice and human agency disregarded even the basic discoveries of late-19th-century sociology: that in any mass society, life chances are unevenly distributed, there are permanent winners and losers, a minority dominates the majority, and the elites are prone to manipulate and deceive.
The two important basic discoveries of the century — relativity and quantum mechanics — have not been assimilated by people.
If one assumes that funding for HIV/AIDS was right sized to enable translation of basic discoveries to successful therapies, then given the lack of effective AD therapies, one possible implication is that funding for AD has been insufficient.
Creation of NCATS would speed the translation of basic discoveries to real world applications and ensure that we are focused on the end goal of our investment in research: treatments and cures.
The translation of basic discoveries to commercially viable tissue-engineered/regenerative medicine products poses scientific, regulatory, and economic challenges.
However, as the field has developed, the NIH has responded proactively to identify roadblocks and to develop solutions that will accelerate translation of basic discoveries to the clinical setting.
In brief, this scientific statement assesses the current timeline for effective translation of basic discoveries to clinical advances, highlighting past successes.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com