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The puzzle of LMNA cardiomyopathy highlights the need to foster the education and training of physician-scientists who can translate basic discoveries based on cell biology, genetics and animal model research into treatments for human patients.
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Scientific discoveries based upon the curiosity of the individual are crucial for fundamental advances in knowledge.
Discovery, based in Bethesda, Md., has four shareholders.
Is my "discovery" based on white acceptance?
Basic discoveries have been put to use quickly in the animal industries.
In his view "the chain from basic discoveries to consumer products is long, obscure and slow – but destroy the basics and the whole chain will collapse".
Basic discoveries still need to be made.
In fact, he believes, industry funding is vital for translating basic discoveries into clinical therapies.
"Their goal is to make basic discoveries and to publish important research papers," Scheller notes.
Basic discoveries will remain the lifeblood of clinical development.
However, without basic discoveries, there will be nothing to "translate".
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