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The basic design to study the substrates of transporters is to determine the uptake of a selected test substance into a cell line that expresses the transporter of interest in comparison to the same cell line lacking the transporter.
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Study methods: basic design of the study (prospective cohort or historical cohort with data collection based on medical records or case-control study), time span between index test and reference test, treatment between index test and reference test.
The basic design of the study was straight-forward: a prospective cohort study among 7,983 persons living in the well-defined Ommoord district in the city of Rotterdam in the Netherlands (78% of 10,215 invitees).
The basic design of the study is straight-forward: a prospective cohort study among, initially, 7,983 persons living in the well-defined Ommoord district in the city of Rotterdam in The Netherlands (78% of 10,215 invitees).
The basic design of the study was a randomized, double-blind, placebo-controlled study lasting three months.
"You have to use your knowledge of the field and judge the scientific novelty and the basic design of the study," Sambunjak says.
The basic design of our study is as follows (Figure 1).
JSA planned basic design of the study and coordination.
YK and YS participated in the basic design of this study and coordination.
The basic design of the study has been secondary analysis of the data available through World Bank LSMS.
AC contributed to study design and management, basic analysis and drafted the manuscript.
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