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Results Receiver operating characteristics curves for the basic clinical assessment model alone and with the results of resting ECGs were superimposed with little difference in the C statistic.

In the cohort, receiver operating characteristics curves for the basic clinical assessment model alone and with iteration for the resting ECG were effectively superimposed with little or no increment in the C statistic (fig 2).

With the exercise ECG iterations the C statistic (95% confidence interval) for the basic clinical assessment model increased in the summary ECG subset from 0.69 (0.65 to 0.73) to 0.74 (0.70 to 0.78) and in the detailed ECG subset from 0.69 (0.62 to 0.77) to 0.76 (0.70 to 0.82).

In the basic clinical assessment model the variables of typical chest pain, age, diabetes, and being male were independently associated with an increased risk of the composite end point of death due to coronary heart disease or non-fatal acute coronary syndrome.

With the iterations for the exercise ECGs the C statistic for the basic clinical assessment model increased in the summary ECG subset from 0.70 (95% confidence interval 0.68 to 0.73) to 0.74 (0.71 to 0.76) and in the detailed ECG subset from 0.74 (0.70 to 0.79) to 0.78 (0.74 to 0.82).

When analysis was restricted to patients with an intermediate probability of coronary artery disease 20-800%), the receiver operating characteristics curves for the basic clinical assessment model alone and with iteration for the resting ECG remained effectively superimposed, reflecting poor discrimination.

We then used the covariates that remained statistically significant at the 5% level in each model to build three incremental models: basic clinical assessment, basic clinical assessment plus resting ECG, and basic clinical assessment plus resting ECG plus either summary exercise ECG or detailed exercise ECG.

The next few years witnessed increasing sophistication in the techniques used to diagnose brain death, none of which, however, surpassed basic clinical assessment.

Following a more basic clinical assessment, she performed RDTs on all suspected malarial cases and collected 2 blood slides and a filter paper blood spot.

Conclusion In ambulatory patients with suspected angina, basic clinical assessment encompasses nearly all the prognostic value of resting ECGs and most of the prognostic value of exercise ECGs.

More of the epidemiological models had been externally validated than the more recent clinical assessment models.