The major questions linking obesity to type 2 diabetes that need to be addressed by combined basic, clinical, and population-based scientific approaches include the following: 1) Why do not all patients with obesity develop type 2 diabetes?
To tackle the scientific bottlenecks to key translational opportunities, new horizontally integrated organizations of experts in basic, clinical and quantitative research are needed.
Although the clinical and scientific applications of the approach are currently hindered by basic gaps in our understanding of the anatomy and physiology of the ductal lobular systems, they have significant potential.
With advances in clinical and scientific knowledge, changes in diagnostic systems are inevitable.
Even the basic clinical question if physical activity would be beneficial or harmful for affected patients cannot be answered on the basis of the available clinical and scientific literature.
Our editorial team of Lyn Reynolds, Shannon Potts, Jane Lucas, Rita Summers, and Amanda Nixon now work with not only Diabetes Care but also Diabetes, thus fulfilling the ADA's important role in the dissemination of the best basic and clinical scientific information in an efficient and user-friendly manner.
Factors such as diet, increased body mass and obesity have been studied in both clinical and basic scientific research, as they relate to osteoarthritis onset and progression.
However, clinical and basic scientific research focusing on therapeutic strategies for CF-associated chrhinosinusitisusitis (CRS) lags behind the evidence-based approaches currently used for pulmonary disease.
In the last decades, some advanced MRI techniques, such as diffusion weighted imaging (DWI), diffusion tensor imaging (DTI), and blood oxygen level dependent functional MRI (fMRI), have been widely used in the clinical and basic scientific studies.
