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Members of these families may be involved in more basic cellular processes and less in processes associated with responses to stress43.
These findings are of general importance for understanding basic cellular processes and have contributed to our knowledge of the underlying mechanisms of immunoregulatory abnormalities that arise in autoimmune diseases.
They noted that housekeeping genes define basic cellular processes and could be used as a reference standard but paradoxically mentioned that maintenance/housekeeping genes exhibit unique patterns for each specific tissue type.
These RNAs, ~22 nucleotides in size, act as sequence guides that direct Argonaute protein complexes to mRNAs, where they decrease protein synthesis through translational repression or mRNA degradation and thereby influence many basic cellular processes and diseases [ 52- 58].
miRNAs are involved in the regulation of most basic cellular processes and are also implicated in tumorigenesis where they act as oncogenic or tumor suppressing miRNAs (reviewed by Hwang and Mendel).
The budding yeast, Saccharomyces cerevisiae, has been an excellent eukaryotic model system for understanding basic cellular processes and metabolic pathways [ 1]. S. cerevisiae was the first eukaryotic genome for which the genome sequence was reported [ 2].
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The other missing genes are involved in basic cellular processes, translation and ion homeostasis.
In contrast, the stable genes were primarily related to basic cellular processes, including protein and macromolecular syntheses and transport.
Due to the high degree of conservation of basic cellular processes between yeast and higher eukaryotes, and to the existence of an ancestral PCD machinery in yeast, yeasts are an attractive tool for the study of affected pathways that give insights into the mode of action of both antitumour and antifungal drugs.
A BTA1 region 220 kb upstream of FKBP2, which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking, was highly significant for fat yield, protein yield and protein percentage.
According to previous work concerning the best reference genes for transcription normalization in plants, the most reliable ones are those constitutively expressed and involved in basic cellular processes, such as protein and sugar metabolism and cell structure [ 18, 20- 22].
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