Other genes present are involved in basic cellular functions such as acetyltransferases, involved in posttranslational modifications of ribosomal proteins, the functional significance of which remains unclear but may have regulatory roles (Nesterchuk et al. 2011).
Growing oocytes are dependent on GC for basic cellular functions, such as the provision of amino acids and metabolic substrates [19] [22].
IRS molecules are key mediators of insulin signalling and play a central role in maintaining basic cellular functions such as growth, survival and metabolism.
Indeed, suppression of angiogenesis with relatively high doses of calpain inhibitors is not surprising given the importance of calpain activity for basic cellular functions such as adhesion and migration [7], [8], [38], [39].
Therefore, we investigated the key signalling pathways, PI3K/Akt and MAPK/ERK, which are involved in AP-1 activation [30], [31] and play a pivotal role in basic cellular functions such as cell growth, survival, migration, angiogenesis and tumorigenesis [28], [29], [42].
Aneuploidy would be expected to have dramatic consequences on basic cellular functions such as proliferation.
Post-translational modifications of proteins regulate a wide variety of basic cellular functions in fungi, such as cellular growth, adaptive and developmental processes.
Many of these therapies focus on proteins that are involved in cell signalling pathways, which form a complex communication system that governs basic cellular functions and activities such as cell division, cell movement, how a cell responds to specific external stimuli and even cell death.
In some studies, gene expression and basic cellular function of such ALI cultures were shown to resemble those found in vivo in intact bronchial epithelium [ 1, 17].
BP terms underrepresented among 2ROs (Additional file 5, Table S3_bp) were dominated by basic cellular functions strongly conserved throughout Eukaryota, such as translation, DNA repair, RNA splicing, DNA replication, protein folding, DNA recombination, cellular respiration, mRNA transport or ubiquitin-dependent protein catabolic process.
A previous study showed that the establishment of endocytosis was a crucial process involved in many diverse aspects of plant life, such as basic cellular functions, growth development, and hormonal signaling (Fan et al. 2015).
