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A better understanding of this mechanism will enable devising better tools for the generation of transgenic plants and will further enrich our knowledge of basic cellular functions and host pathogen interactions.
Cilia-dependent signaling affects very basic cellular functions and aspects including cellular polarity and cell cycle progression [1-3].
The study had tested 11 potential RGs, in 6 tissues, which are involved in the maintenance of basic cellular functions and thus are assumed to be constitutively expressed at constant levels.
Many miRNAs cloned from chicken embryos were previously reported to be ESC-specific in the mouse and human, indicating their contribution to basic cellular functions and maintenance of pluripotency [29].
A generally accepted view of gene expression programs divides genes in two main categories: i) housekeeping genes that are virtually always expressed in every tissue and work to maintain basic cellular functions; and ii) genes whose expression is preferential in one or a few tissues and which provide specialized functions that have a strong effect on the physiology of the whole organism.
The most prominent overrepresented gene expression features in our dataset pointed toward (changes in) basic cellular functions and disease.
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These patterns contrast the processes for the maintenance of basic cellular functioning and those required for adaptation.
Genes with large epistatic effects interact strongly across the genome and tend to be involved in basic cellular function and maintenance (supplementary table S3, Supplementary Material online).
Housekeeping genes were defined as the constitutive genes that were required for the maintenance of basic cellular function, and were expressed in all cells of an organism.
The striking difference in genome size and thus in several metabolic and basic cellular functions between CRt and CLEAA might perhaps instead be explained by other factors.
The information obtained by combining multiple markers offers a means with unprecedented power to further advance our understanding of the most basic cellular functions (proliferation, death, and differentiation) and how these functions may be optimized or modulated by an external signal such as a treatment.
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