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The majority of phosphorylated peptides was phosphorylated to similar levels in all treatments, and supposedly represent general peptides that detect kinase activities involved in basic cellular functioning [29].
Such sequence and structural conservation implies that LAMR is important for basic cellular functioning.
These patterns contrast the processes for the maintenance of basic cellular functioning and those required for adaptation.
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Indeed, over-represented functional classes of constitutively expressed genes are mainly basic cellular functions, expected to be active in each cell type, such as metabolism or gene expression related functions.
Other genes present are involved in basic cellular functions such as acetyltransferases, involved in posttranslational modifications of ribosomal proteins, the functional significance of which remains unclear but may have regulatory roles (Nesterchuk et al. 2011).
Defective mitochondria are swapped out for healthy ones, but mitochondrial DNA governs only a handful of basic cellular functions.
Researchers have discovered how mutations in genes required for basic cellular functions give rise to face-specific birth defects.
Hence PREP1 is not, or not only, a developmentally essential gene, but it also controls basic cellular functions, like DNA replication timing.
There is increasing evidence that basic cellular functions are sensitive not only to radiation but also to microgravity.
Monitoring the level and dynamics of ATP in living organisms contributes to better understanding of basic cellular functions.
We propose that organisms rely on a dynamic enhancer landscape to control basic cellular functions in a tissue-specific manner.
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