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The best-suited candidates should have strong communication skills and solid training in the use of a wide range of basic cellular and molecular biology techniques.
First, we sought to expand our understanding of the proteins involved in biomineralization in the sea urchin, a powerful model system for analyzing the basic cellular and molecular mechanisms that underlie this process.
The basic cellular and molecular processes underlying pacemaking are a major target of cardiac therapies.
In spite of this, current information is insufficient to completely understand the basic cellular and molecular mechanisms underlying DEs.
Such analyses provide basic cellular and molecular information regarding pathways involved in neuronal-glial interactions as well as information that may be helpful in clinical decision making.
The majority of work in these centers focuses on basic cellular and molecular biological processes, areas that are mainstays of research at NIGMS.
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However, many basic cellular features and molecular processes of the disease are poorly understood.
These controversial effects of riluzole in clinical application and animal research call for simplified model systems to explore its basic mechanisms at cellular and molecular levels.
In addition, these findings will contribute to our basic understanding of the cellular and molecular events involved in the formation, maintenance and plasticity of the neuromuscular synapse.
It is our opinion, however, that development of nanoparticles as tools for basic science may revolutionize cellular and molecular biology techniques as much as understanding and utilization of enzymatic reactions did, leading to creation of molecular biology we know today.
No model is ideal, but the most useful are those that reflect the natural history and histopathology of human disease, and allow for basic investigations into underlying cellular and molecular mechanisms.
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