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Genes with decreased expression were mainly involved in basic cellular activities and the associated regulatory infrastructure, such as RNA processing and splicing (fibrillarin, PNP1ase), translation (eIFs, NOP56, RPSOB), morphogenesis (expansins, nodulins, cell wall proteins), or essential metabolism genes, e.g., during nutrient-induced reprogramming [118].
Conserved genes are involved in basic cellular activities and thus are required for all stages.
Some of these, such as the eukaryotic translation factors (EIF2, EIF4, EIF5), histone H4i, the lysosomal proteon pump ATP6V1E1, the peroxisomal biogenesis factor 6, asparagine synthetase, ER/Golgi transport (Rab1B), and chromobox homolog 3 participate in basic cellular activities and reflect the relatively generalized state of naïve stem cells.
Similar(57)
The protein kinase family is one of the largest protein families in human, comprising 518 different kinases that function as on/off switches in cellular signaling pathways and modulate almost all basic cellular activities.
Here, we identify basic cellular activities connected to translational control of gene expression as sufficient to specify auxin-mediated development.
The study illuminates the integration of small RNA related pathways with other basic cellular activities that govern gene expression for different cellular actions.
Although no definitive function for vault particles has yet been determined, their evolutionary conservation and high abundance suggest that they are involved in one or more basic cellular activities.
The synthesis, enzymatic & cellular activities and pharmacodynamic effects are described.
A result, say the Happylogists, is greater cellular activity and skin repair.
Many of these therapies focus on proteins that are involved in cell signalling pathways, which form a complex communication system that governs basic cellular functions and activities such as cell division, cell movement, how a cell responds to specific external stimuli and even cell death.
These genes were involved in diverse biological processes and those involved in basic cellular, biosynthetic, catabolic, and metabolic activities, as well as responses to stress and signal transduction, were highly enriched.
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