This serves as an important intermediate step for basic and translational studies.
Generation of midbrain dopaminergic (mDA) neurons from human pluripotent stem cells provides a platform for inquiry into basic and translational studies of Parkinson's disease (PD).
The similarities between structure and function of porcine, canine, and human pancreata are such that the pig and dog serve as valuable models in basic and translational studies, most recently for efforts aimed at modeling pancreatitis and diabetes, developing functional and sustainable replacement of endocrine functions, and in imaging and manipulation studies.
Developing molecular signatures in particular, is playing an increasingly important role in a variety of research design objectives both in basic and translational studies.
This is quite evident from the relative small number of basic and translational studies currently available in the literature.
Finally, MVaf expression attenuated B16-F10 solid tumor growth in mice, suggesting that this peptide may be useful as an apoptosis-inducing tool for basic and translational studies.
Two recent SS2 outbreaks in China not only seriously challenged public health but also shocked the scientific community, calling for the basic and translational studies of S. suis.
Readers will find basic and translational studies that explore the immunologic basis of allergic rhinitis (AR) and chronic rhinosinusitis (CRS), as well as clinical and technical studies that explore issues ranging from rhinoscleroma to cerebrospinal fluid leak repair.
In vivo experiments are currently the gold standard in basic and translational studies; however several factors generally hinder the utility of animal models to dissect out the impact of complex pathophysiological stimuli down to molecular mechanisms.
Thus, in contrast to other models, such as MMTV-PyMT and MMTV-wnt1, in which pooling individual mouse tumors can generate sufficient material for basic and translational studies [ 16, 42], Brca1 tumors will need to be analyzed individually and these studies are limited by the size of each original tumor.
