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(Given one mutation, is the next mutation on the same strand similar?) There were six clones with mutations at only purine or pyrimidine bases on one strand, and six clones with mutations to both purine and pyrimidine bases on the same strand.
Dinucleotide substitutions were identified when two substitutions were present in consecutive bases on the same chromosome (sequence context was ignored).
Based on our whole blood mRNA-seq datasets, the fraction of overlapping nucleotide bases on the same and opposite strands were estimated at 2.94 % and 3.1 %, respectively.
Deoxyribodipyrimidine photolyases catalyze the light-dependent monomerization (300 600 nm) of cyclobutyl pyrimidine dimers, which are formed between adjacent bases on the same DNA strand upon exposure to UV radiation [ 34– 34].
Then we multiplied the expected number of nucleotides by the average genomic mutation rate, to give the GC normalized mutation rate (U), which was used to plot the topology: U = (U 1 μ ¯ 1 + U 2 μ ¯ 2 ) × μ. "Context" refers to the single 5′ and 3′ flanking bases on the same strand as a focal base, recognizing that a G C base pair is not equivalent to a C G base pair.
This in turn can lead to defective protein synthesis by virtue of the altered sequence of DNA bases on the same strand of the DNA molecule.
Similar(52)
The other charts — think of them as the Romney ones — are based on the same data.
Given that similarity, one might assume that they're based on the same technology.
The case for HS2 is based on the same thinking.
Both conclusions are based on the same standard of evidence.
"I built my country based on the same solid principles".
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