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In addition, this functional comparison permitted the identification of regulatory regions that would have been impossible to identify only on the bases of sequence comparison.
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The molecular epidemiology of PPRV, which is based on sequence comparison of a small region of the fusion (F) gene (322 nt) or the nucleoprotein (N) gene (255 nt), has identified 4 distinct lineages (I IV) of PPRV (2 ).
Based on sequence comparison of the chloroplast genome of P. argentatum with H. annuus and L. sativa, two inversions of 22,890 bp and 3,364 bp were observed in P. argentatum, similar to those described by Kim et al. [ 14] and Timme et al. [ 22].
Here we predict 3D structure of CVB3 2Apro based on sequence comparison and homology modeling with human rhinovirus 2Apro.
Based on sequence comparison of homologous pasteurellacean genes, DUESs were suggested to evolve by gradual accumulation of point mutations in preexisting sequences rather than by insertion/deletion of entire sequences [15].
This classification reflects the phylogenetic relationships between ABC proteins, allowing an assignment into structural classes based on sequence comparison of their NBF motifs.
Based on sequence comparison of over 40 kb across a 15-Mb region on chromosome 12, M. spretus strains are more closely related to each other than to the Swiss-inbred strains of M. musculus.
GO semantic similarity measures are tools that can be used to develop efficient and reliable strategies that allow function inference of uncharacterized proteins based on sequence comparison, microarray data analysis, or interaction networks.
Based on sequence comparison, three types of flexible arms, termed the zinc-dependent phosphodiesterase (ZiPD -, ELAC2- and Thermotoga maritima (TM -type flexible arms, have been found in TM -types.
Our previous study provided the functional identification of putative unique transcripts based on sequence comparison, and contributed to linking in silico expression profile data with previous information about biological processes occurring throughout the fungal life cycle [ 14].
The extreme AT bias (above 80%), the high amino-acid bias (six amino acids account for more than 50% of the protein composition), and the presence of a large number of low-complexity regions that are believed to form unstructured segments [ 7], can impede the efficacy of standard methods of sequence comparison based on BLAST [ 8, 9] or HMMER [ 10].
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