Sentence examples for bases of common complex from inspiring English sources

The major objective of the HUFS was to enroll and examine a randomly-ascertained sample of African American families, along with a set of unrelated individuals, for the study of the genetic and environmental bases of common complex diseases including hypertension, obesity, diabetes and associated phenotypes.

This approach is ignoring the complexity of common complex diseases.

The field has progressed from comparatively small studies of rare genetic diseases to vast consortia based efforts that target the inherited components of common complex diseases and which typically involve thousands of individual samples.

They do not support the promulgation of commercial DNA based tests nor the search for gene variants that confer increased risk of common complex diseases on the basis that they effectively motivate health related behaviour change.

The existing evidence provides no support for the claim that the receipt of results from DNA based tests for gene variants that confer increased risk of common, complex diseases motivates behaviour change.

"People have volunteered to participate anonymously in studies which explain some of the genetic explanations of common complex disease".

In general, only 1.5%50%% of heritability of common complex diseases and traits can be explained by common variants [16].

They no longer have a base of common religious tradition.

The intervention was based on a feasible health service model for communication of risks associated with common, complex conditions.

For validation of our rank based gene prioritization approach, we selected PD, another common complex neurodegenerative disorder that involves the deposition of α-synuclein as intracellular Lewy bodies leading to progressive degeneration of dopaminergic neurons within multiple brain regions.

However, even with these limitations, we believe valuable insights can be gained from broad based literature assessments of the genetic contribution in human common complex disease and in mouse phenotypic biology.