Sentence examples for bases at a position from inspiring English sources

A specific frequency ratio was calculated by dividing the ratio of variant calls/number of all the bases (at a position) by the ratio of variant allele quality sum/quality sum of all bases.

In both cases, the entire HIV genome was recovered with unprecedented levels of coverage (number of mapped bases at a position in the genome) compared to previous reports.

If >80% of the bases at a position were the same, this base was used as the consensus base.

Likelihood function: consider the aligned bases at a position from M species, denoted by (x1,…, x M ).

An abundance of non-reference bases at a position called by the posterior density test may be due to a true mutation or due to a random sequencing error; we would like to differentiate these two scenarios.

In this way we generally penalize less for mismatches at positions with less confident base calls, but also are sensitive to situations in which the base caller has difficulty deciding between two bases at a position.

If >80% of reads had an alternative base at a position, we assigned a variant.

The most frequent base at a position was chosen for the consensus sequence.

Additionally, we required both parents to uniformly exhibit a single base at a position (no secondary base call).

If the consensus base at a position receives a score of 40, and all others receive scores of −40, then a mismatch at that position will be equated with a score penalty of 1.

This control over the mutation enables particular types of mutation to be made by using mixed base codons, i.e. codons that contain a mixture of bases at a specified position (e.g. N denotes an equal mixture of A, T, G or C at a single position).