Sentence examples for bases at a given from inspiring English sources

For continuity of coverage calculations, the GATK's Depth of Coverage walker was used to calculate the number of bases at a given position in the genomic alignment.

Because different bases at a given genome position may support the same polymorphism (e.g., two types of mutation are transversions), some positions contributed multiply to some vectors.

The proportions of methylated and unmethylated bases at a given position were then compared between groups of reads carrying each allele at the corresponding heterozygote site using a Fisher's exact test.

The pattern [AG]NNATGG (where N is any nucleotide, and letters in square brackets indicate alternative bases at a given position) was used, derived from published data on initiator codons from highly curated sequences [ 15].

In our view, the kpol measurements are on firm foundation as they are based on equilibrium properties, the states of ionization of acids and bases at a given pH, based on the reasonable assumption that the actual chemical transformation (bond making/breaking) is slow compared with ionization equilibration.

Depending on the identity of the base at a given SNP, a different dye (or hapten) -conjugated chain-terminating dideoxynucleotide is added to the 3'-end the oligonucleotide.

The ethical issues will be specific only for the knowledge base at a given time and for a specified production and use scenario.

Quality scores are usually assigned separately for each base at a given read position, but may be summarized as a score for the position itself (generally measuring confidence in the called base at that position).

Using a Hidden Markov Model, that study found that a useful level of complexity was four states with the probability of a base at a given position depending on the state and the previous base.

The deduced CDR3 nt sequences were then scanned using the Phred quality score cutoffs of 0, 10, 20 or 30 [ 24], and reads with CDR3 nt sequence containing at least one low-quality base at a given cutoff level were filtered out.

To detect significant polymorphisms, that is likely polymorphisms per se, we calculated probabilities with the same parameters, save that k = number of deviant reads supporting a particular base at a given position and P = 0.0001/3 because only one of three possible mutations was considered (fig. 1).