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Since for such a scenario three baselines need to be correlated, moderate upgrades at the correlation centers might be required, whereas hardly any modification in the post-processing chain are necessary.
Furthermore, baselines need to be established for key environmental indicators such as groundwater quality prior to any exploitation.
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In addition to using the HHT for de-noising, the baseline needs to be adjusted.
Furthermore, the baseline needs to be stable, with as little variability as possible, for the sake of validity.
To obtain accurate CT values, the baseline needs to be set at least two cycles earlier than the CT value for the most abundant sample.
Thus no general differences between ADHD and control children in cortisol level at baseline needed to be taken into account in the analysis.
Consequently, the application of dynamic modelling baselines would need to be accompanied by transparent documentation of their underlying assumptions.
Presenting the results in the form of Fig. 3, combines relevant information that is required to help make decisions on whether the daily baseline values need to be updated.
Therefore, as a first step, baseline studies need to be carried out on knowledge, attitude, and practices regarding oral health.
Before launching a risk of bias assessment, therefore, reviewers need to discuss which baseline characteristics need to be comparable between the groups.
The data that are gathered during the baseline condition need to be stable (absence of a trend), or with a trend that is in the opposite direction to the expected effect of the independent variables.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com