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Exact(9)
The primary endpoint of change in modified Rodnan skin score (mRSS) from baseline will be assessed at 52 weeks, as will be secondary endpoints such as mRSS progression and regression rates, patient quality of life, digital ulcer burden, and change in forced vital capacity and carbon monoxide diffusing capacity.
Brain development at baseline will be assessed using advanced MRI techniques to qualitatively assess cerebral structure.
Finally, changes from baseline will be assessed by a linear mixed-effects model using linear contrasts.
Simple changes from baseline will be assessed at each time point using t-tests or corresponding nonparametric tests.
Secondary outcomes, such as changes of PPQ scores and Unified Parkinson's Disease Rating Scale scores from baseline will be assessed.
General health and habitual physical activity at baseline will be assessed by a questionnaire devised by the research group.
Similar(51)
The baseline measures will be assessed prior to randomisation and further assessments will be conducted 4 and 12 months after randomisation.
Baseline measures will be assessed prior to randomisation.
Baseline comparability will be assessed by descriptive statistics to determine whether randomization was successful.
A range of baseline measures will be assessed as potential moderators of outcomes.
Analyses will be undertaken using STATA [ 43] and comparability of baseline characteristics will be assessed for participants in both groups.
More suggestions(15)
indicators will be assessed
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baseline will be summarized
baseline will be retested
baseline will be followed
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baseline will be produced
baseline will be repeated
baseline will be used
baseline will be conducted
baseline will be provided
baseline will be performed
baseline will be raised
baseline will be presented
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