Change in LIC was more pronounced in patients with higher baseline LIC which may reflect either higher dose of deferasirox used or a potentially increased molecular efficiency of the chelator in severely iron overloaded patients.
There was an interaction between change in PaO2/FiO2 and the etiology of ARDS, with a greater change in PaO2/FiO2 for patients with extra-pulmonary ARDS, independent of baseline PaO2/FiO2, which may reflect the different degree of lung recruitability.
It is important to note baseline IGF1 levels, which may reflect responsiveness to somatostatin analogues, when considering EDI; patients with baseline levels below but close to the ULN may be less suitable candidates who require more careful consideration.
However, relatively high levels of pro-apoptotic genes were observed at baseline in NRVMs, which may reflect stresses sustained by the cells when grown in culture.
At baseline, the PO/RPM ratio, which may reflect PO adequacy to preload status, was not different between the two groups.
The mean copeptin-us plasma concentration was elevated compared to baseline up to 3 h post-exercise, which may reflect chronic percentage of plasma volume vasopressin secretion under conditions of endurance exercise (Hew-Butler et al., 2011).
Only 40%to50%0% of patients were thus retained in the analysis but these patients were comparable to those excluded according to baseline characteristics except there was an age effect which may reflect a selection bias.
However, we found no significant correlation between change in radiographic progression and change from baseline in concentrations of MMP-3 for adalimumab patients in the Canadian study, which may reflect the small sample size.
Baseline p38 MAPK mRNA expression level evaluated by realtime PCR is higher in C57BL/6 than NZW, which may reflect higher total p38 MAPK level evaluated by IHC in C57BL/6 than in NZW.
Iron increase correlated across several ROIs, which may reflect an underlying age-related process.
