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Improvements from baseline were observed with both treatments.
Similar significant reductions in SBP from baseline were observed with nebivolol and losartan.
Significant decreases in mean DBP and SBP from baseline were observed with nebivolol monotherapy (−15.0 and −14.8 mmHg, respectively) and nebivolol plus diuretic (−12.0 and −16.2 mmHg, respectively).
For the 2 weeks of the crossover period (visit 5 and visit 6), significant reductions in ADHD-RS-IV total and subscale scores from baseline were observed with LDX compared with placebo (by difference in LS means; P <.0001).
Similar improvements from baseline were observed with FF 200 μg and 100 μg, respectively, for PEF (L/min) measured in the evening (7.2, 5.9) and in the morning (13.2, 13.4) (Table 4).
Significantly greater (p < 0.05) improvements in all of the secondary outcome measures (vs. baseline) were observed with the formoterol 4.5 and 9 μg bid groups compared with those seen in the placebo group (Tables 2 and 3).
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This is supported by the exploratory observation that a higher increase in Hb from baseline was observed with dosing of ≥1,000 mg of iron isomaltoside 1,000.
A small, gradual decrease from baseline was observed with sitagliptin, which also plateaued after week 34.
A modest, although statistically insignificant, increase in migrated monocytes over baseline was observed with antibody neutralization.
No difference from baseline was observed with any pain assessment scale at 1 hour and 24 hours (Table 1).
In this study, significantly greater FPG reduction from baseline was observed with vildagliptin versus voglibose [1.34 vs. 0.4 mmol/l (24.1 vs. 7.8 mg/dl); p < 0.001].
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