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The four responders at baseline were not fluid-responsive at T1 (PPV < 12%).
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Moreover, approximately half of the patients included in this study were not fluid responsive.
Prone position increased cardiac output in patients found to be volume responsive prior to the maneuver; however, this benefit was absent in patients who were not fluid responsive [20].
In contrast, we observed that patients with both systolic dysfunction and inability to dilate, were not fluid responsive.
In other words, patients who were proven to be not fluid responsive continued to receive the same amount of subsequent fluid boluses as did fluid responsive patients.
The identification of a dominant dUp, although rare, may suggest that the patient is not fluid responsive and that the mechanical breath is in fact assisting LV ejection.
However, studies conducted during the past few years have shown that about 50% of critically ill patients do not exhibit the desired effect (they are not fluid responsive) [ 1].
Furthermore, a volume challenge is not fluid resuscitation; it is merely a test to identify those who are preload responsive [ 35].
Klein's answer is not fluid.
Memory isn't fluid, you see.
Similarly, in PRISM, there was no relationship between CVP and cardiac output before or after fluid resuscitation, and almost 40% of those patients with a CVP of not more than 0 cm H2O were not volume-responsive [ 19].
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