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Changes in adjusted scores between successive interviews and from baseline were also calculated from these estimates.
The overall means and standard deviations for each outcome variable at baseline were also calculated.
Mean changes and mean percentage changes from baseline were also calculated, together with 95% confidence intervals to assist interpretation.
In addition, the ratio of grip strength post-treatment and baseline were also calculated and changes were presented as a percentage of baseline value.
The AUROC for APACHE II score and pre-DIC scores (by ISTH non-overt DIC, and JAAM acute DIC criteria) at baseline were also calculated for comparison.
Changes in blood glucose from the 0 min baseline were also calculated and the area over the baseline (0 min) value calculated using a rhomboid rule for the time periods 0 180 min, 0 30 min, and 30 180 min.
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In addition, the ratio of grip strength after treatment to baseline was also calculated, and changes were presented as percent of baseline.
Charlson Co-morbidity Index 28 at baseline was also calculated using a technique described by Khan et al. 29 This index is calculated based upon the presence or absence of 19 weighted comorbid conditions, including history of diabetes which was, therefore, not separately included in the multivariate analysis.
Because follow-up information is used when applying this method, stratified analyses for baseline dosage were also calculated (Fig. 1).
The percentage of patients without anxiety (HAM-A ≤ 9) and the percentage considered to be responders (HAM-A reduction ≥ 50% compared with baseline score) were also calculated.
The changes in these measurements from the baseline (ΔCt) were also calculated as (Ct-Cb), with Ct and Cb being the outcome measurements at specific time points, and at baseline if data were available.
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